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Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H). (opens new window)

Alshryda S, Mason J, Sarda P, Nargol A, Cooke N, Ahmad H, Tang S, Logishetty R, Vaghela M, McPartlin L, Hungin AP.

Forrás‎: J Bone Joint Surg Am 2013;95(21):1969-74.

Azonosító‎: PubMed 24196467

DOI‎: 10.2106/JBJS.L.00908

https://www.ncbi.nlm.nih.gov/pubmed/24196467 (opens new window)

Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total knee replacement: a randomized controlled trial (TRANX-K). (opens new window)

Alshryda S, Mason J, Vaghela M, Sarda P, Nargol A, Maheswaran S, Tulloch C, Anand S, Logishetty R, Stothart B, Hungin AP.

Forrás‎: J Bone Joint Surg Am 2013;95(21):1961-8.

Azonosító‎: PubMed 24196466

DOI‎: 10.2106/JBJS.L.00907

https://www.ncbi.nlm.nih.gov/pubmed/24196466 (opens new window)

Multimodal patient blood management program based on a three-pillar strategy: a systematic review and meta-analysis. (opens new window)

Althoff FC, Neb H, Herrmann E, Trentino KM, Vernich L, Füllenbach C, Freedman J, Waters JH, Farmer S, Leahy MF, Zacharowski K, Meybohm P, Choorapoikayil S

Forrás‎: Ann Surg 2019;269(5):794-804.

Azonosító‎: PubMed 30418206

DOI‎: 10.1097/SLA.0000000000003095

https://www.ncbi.nlm.nih.gov/pubmed/30418206 (opens new window)

Effect of epsilon aminocaproic acid on red-cell transfusion requirements in major spinal surgery. (opens new window)

Berenholtz SM, Pham JC, Garrett-Mayer E, Atchison CW, Kostuik JP, Cohen DB, Nundy S, Dorman T, Ness PM, Klag MJ, Pronovost PJ, Kebaish KM.

Forrás‎: Spine 2009;34(19):2096-103.

Azonosító‎: PubMed 19730217

DOI‎: 10.1097/BRS.0b013e3181b1fab2

https://www.ncbi.nlm.nih.gov/pubmed/19730217 (opens new window)

The combined use of oral and topical tranexamic acid is a safe, efficient and low-cost method in reducing blood loss and transfusion rates in total knee arthroplasty. (opens new window)

Cankaya D, Dasar U, Satilmis AB, Basaran SH, Akkaya M, Bozkurt M.

Forrás‎: J Orthop Surg 2017;25(1):2309499016684725.

Azonosító‎: PubMed 28176599

DOI‎: 10.1177/2309499016684725

https://www.ncbi.nlm.nih.gov/pubmed/28176599 (opens new window)

An evaluation of the use of topical tranexamic acid in total knee arthroplasty. (opens new window)

Chimento GF, Huff T, Ochsner JL Jr, Meyer M, Brandner L, Babin S.

Forrás‎: J Arthroplasty 2013;28(8 Suppl):74-7.

Azonosító‎: PubMed 24034510

DOI‎: 10.1016/j.arth.2013.06.037

https://www.ncbi.nlm.nih.gov/pubmed/24034510 (opens new window)

Hemostatic techniques reduce hospital stay following multilevel posterior cervical spine surgery. (opens new window)

Cho SK, Yi JS, Park MS, Hu G, Zebala LP, Pahys JM, Kang MM, Lee DH, Riew KD.

Forrás‎: J Bone Joint Surg Am 2012;94(21):1952-8.

Azonosító‎: PubMed 23138237

DOI‎: 10.2106/JBJS.K.00632

https://www.ncbi.nlm.nih.gov/pubmed/23138237 (opens new window)

Comparing ε-aminocaproic acid and tranexamic acid in reducing postoperative transfusions in total knee arthroplasty. (opens new window)

Churchill JL, Puca KE, Meyer E, Carleton M, Anderson MJ.

Forrás‎: J Knee Surg 2017;30(5):460-6.

Azonosító‎: PubMed 27699724

DOI‎: 10.1055/s-0036-1593362

https://www.ncbi.nlm.nih.gov/pubmed/27699724 (opens new window)

Process improvement project using tranexamic acid is cost-effective in reducing blood loss and transfusions after total hip and total knee arthroplasty. (opens new window)

Demos HA, Lin ZX, Barfield WR, Wilson SH, Robertson DC, Pellegrini VD Jr.

Forrás‎: J Arthroplasty 2017;32(8):2375-80.

Azonosító‎: PubMed 28343823

DOI‎: 10.1016/j.arth.2017.02.068

https://www.ncbi.nlm.nih.gov/pubmed/28343823 (opens new window)

Comparing cost, efficacy, and safety of intravenous and topical tranexamic acid in total hip and knee arthroplasty. (opens new window)

DiBlasi JF, Smith RP, Garavaglia J, Quedado J, Frye BM, Dietz MJ.

Forrás‎: Am J Orthop 2016;45(7):E439-43.

Azonosító‎: PubMed 28005108

https://www.ncbi.nlm.nih.gov/pubmed/28005108 (opens new window)

Clinical and cost effectiveness-related aspects of retransfusion in total hip and knee arthroplasty. (opens new window)

Dobosz B, Dutka J, Dutka L, Maleta P.

Forrás‎: Ortop Traumatol Rehabil 2012;14(5):421-8.

Azonosító‎: PubMed 23208933

DOI‎: 10.5604/15093492.1016367

https://www.ncbi.nlm.nih.gov/pubmed/23208933 (opens new window)

The safety, efficacy, and cost-effectiveness of intraoperative cell salvage in metastatic spine tumor surgery. (opens new window)

Elmalky M, Yasin N, Rodrigues-Pinto R, Stephenson J, Carroll C, Smurthwaite G, Verma R, Mohammad S, Siddique I.

Forrás‎: Spine J 2017;17(7):977-82.

Azonosító‎: PubMed 28323241

DOI‎: 10.1016/j.spinee.2017.03.004

https://www.ncbi.nlm.nih.gov/pubmed/28323241 (opens new window)

Effect of tranexamic acid on transfusion rates following total joint arthroplasty: a cost and comparative effectiveness analysis. (opens new window)

Evangelista PJ, Aversano MW, Koli E, Hutzler L, Inneh I, Bosco J, Iorio R.

Forrás‎: Orthop Clin North Am 2017;48(2):109-15.

Azonosító‎: PubMed 28336035

DOI‎: 10.1016/j.ocl.2016.12.001

https://www.ncbi.nlm.nih.gov/pubmed/28336035 (opens new window)

Saving blood and reducing costs: updating blood transfusion practice in lower limb arthroplasty. (opens new window)

Fenelon C, Galbraith JG, Kearsley R, Motherway C, Condon F, Lenehan B.

Forrás‎: Ir Med J 2018;111(4):730.

Azonosító‎: PubMed 30465599

https://www.ncbi.nlm.nih.gov/pubmed/30465599 (opens new window)

Methods of bloodless care, clinical outcomes, and costs for adult patients who decline allogeneic transfusions. (opens new window)

Frank SM, Pippa A, Sherd I, Scott AV, Lo BD, Cruz NC, Hendricks EA, Ness PM, Chaturvedi S, Resar LMS.

Forrás‎: Anesth Analg 2022;135(3):576-85.

Azonosító‎: PubMed 35977366

DOI‎: 10.1213/ANE.0000000000006114

https://www.ncbi.nlm.nih.gov/pubmed/35977366 (opens new window)

Tranexamic acid decreases blood loss after total shoulder arthroplasty. (opens new window)

Friedman RJ, Gordon E, Butler RB, Mock L, Dumas B.

Forrás‎: J Shoulder Elbow Surg 2016;25(4):614-8.

Azonosító‎: PubMed 26652697

DOI‎: 10.1016/j.jse.2015.09.014

https://www.ncbi.nlm.nih.gov/pubmed/26652697 (opens new window)

Restrictive versus liberal red blood cell transfusion strategy after hip surgery: a decision model analysis of healthcare costs. (opens new window)

Fusaro MV, Nielsen ND, Nielsen A, Fontaine MJ, Hess JR, Reed RM, DeLisle S, Netzer G.

Forrás‎: Transfusion 2017;57(2):357-66.

Azonosító‎: PubMed 28019009

DOI‎: 10.1111/trf.13936

https://www.ncbi.nlm.nih.gov/pubmed/28019009 (opens new window)

Economic impact of tranexamic acid in healthy patients undergoing primary total hip and knee arthroplasty. (opens new window)

Gillette BP, Maradit Kremers H, Duncan CM, Smith HM, Trousdale RT, Pagnano MW, Sierra RJ.

Forrás‎: J Arthroplasty 2013;28(8 Suppl):137-9.

Azonosító‎: PubMed 23886409

DOI‎: 10.1016/j.arth.2013.04.054

https://www.ncbi.nlm.nih.gov/pubmed/23886409 (opens new window)

Cell saver for adult spinal deformity surgery reduces cost. (opens new window)

Gum JL, Carreon LY, Kelly MP, Hostin R, Robinson C, Burton DC, Polly DW, Shaffrey CI, LaFage V, Schwab FJ, Ames CP, Kim HJ, Smith JS, Bess RS; International Spine Study Group.

Forrás‎: Spine Deform 2017;5(4):272-6.

Azonosító‎: PubMed 28622903

DOI‎: 10.1016/j.jspd.2017.01.005

https://www.ncbi.nlm.nih.gov/pubmed/28622903 (opens new window)

Tranexamic acid in patients with cancer undergoing endoprosthetic reconstruction: a cost analysis. (opens new window)

Haase DR, Kimbrel B, Bombardier B, Templeton KJ, Rosenthal HG, Sweeney KR.

Forrás‎: J Am Acad Orthop Surg 2021;29(22):961-9.

Azonosító‎: PubMed 34570739

DOI‎: 10.5435/JAAOS-D-20-00971

https://www.ncbi.nlm.nih.gov/pubmed/34570739 (opens new window)

Topically applied epsilon-aminocaproic acid reduces blood loss and length of hospital stay after total knee arthroplasty. (opens new window)

Harper RA, Sucher MG, Giordani M, Nedopil AJ.

Forrás‎: Orthopedics 2017;40(6):e1044-9.

Azonosító‎: PubMed 28968480

DOI‎: 10.3928/01477447-20170925-07

https://www.ncbi.nlm.nih.gov/pubmed/28968480 (opens new window)

Does tranexamic acid reduce blood transfusion cost for primary total hip arthroplasty? A case-control study. (opens new window)

Harris RN, Moskal JT, Capps SG.

Forrás‎: J Arthroplasty 2015;30(2):192-5.

Azonosító‎: PubMed 25534861

DOI‎: 10.1016/j.arth.2014.08.020

https://www.ncbi.nlm.nih.gov/pubmed/25534861 (opens new window)

Tranexamic acid reduces blood loss and financial cost in primary total hip and knee replacement surgery. (opens new window)

Irisson E, Hémon Y, Pauly V, Parratte S, Argenson JN, Kerbaul F.

Forrás‎: Orthop Traumatol Surg Res 2012;98(5):477-83.

Azonosító‎: PubMed 22854336

DOI‎: 10.1016/j.otsr.2012.05.002

https://www.ncbi.nlm.nih.gov/pubmed/22854336 (opens new window)

Using tranexamic acid for an additional 24 hours postoperatively in hip and knee arthroplasty saves money: a cost analysis from the TRAC-24 randomized control trial. (opens new window)

Karayiannis PN, Agus A, Bryce L, Hill JC, Beverland D.

Forrás‎: Bone Jt Open 2022;3(7):536-42.

Azonosító‎: PubMed 35816170

DOI‎: 10.1302/2633-1462.37.BJO-2021-0213.R1

https://www.ncbi.nlm.nih.gov/pubmed/35816170 (opens new window)

Improved outcomes and reduced costs associated with a health-system-wide patient blood management program: a retrospective observational study in four major adult tertiary-care hospitals. (opens new window)

Leahy MF, Hofmann A, Towler S, Trentino KM, Burrows SA, Swain SG, Hamdorf J, Gallagher T, Koay A, Geelhoed GC, Farmer SL.

Forrás‎: Transfusion 2017;57(6):1347-58.

Azonosító‎: PubMed 28150313

DOI‎: 10.1111/trf.14006

https://www.ncbi.nlm.nih.gov/pubmed/28150313 (opens new window)

Transfusion strategy for primary knee and hip arthroplasty: impact of an algorithm to lower transfusion rates and hospital costs. (opens new window)

Martinez V, Monsaingeon-Lion A, Cherif K, Judet T, Chauvin M, Fletcher D.

Forrás‎: Br J Anaesth 2007;99(6):794-800.

Azonosító‎: PubMed 17928302

DOI‎: 10.1093/bja/aem266

https://www.ncbi.nlm.nih.gov/pubmed/17928302 (opens new window)

A safe, simple and cost-effective protocol for blood transfusion in primary total knee replacement. (opens new window)

Mehra A, Murray J, DeAlwis C.

Forrás‎: Ann R Coll Surg Engl 2004;86(4):260-2.

Azonosító‎: PubMed 15239867

DOI‎: 10.1308/147870804551

https://www.ncbi.nlm.nih.gov/pubmed/15239867 (opens new window)

Are allogeneic transfusions decreasing in total knee arthroplasty patients? National Inpatient Sample 2009-2013. (opens new window)

Mistry JB, Gwam CU, Naziri Q, Pivec R, Abraham R, Mont MA, Delanois RE.

Forrás‎: J Arthroplasty 2018;33(6):1705-12.

Azonosító‎: PubMed 29352682

DOI‎: 10.1016/j.arth.2017.12.014

https://www.ncbi.nlm.nih.gov/pubmed/29352682 (opens new window)

Transfusion cost savings with tranexamic acid in primary total knee arthroplasty from 2009 to 2012. (opens new window)

Moskal JT, Harris RN, Capps SG.

Forrás‎: J Arthroplasty 2015;30(3):365-8.

Azonosító‎: PubMed 25458093

DOI‎: 10.1016/j.arth.2014.10.008

https://www.ncbi.nlm.nih.gov/pubmed/25458093 (opens new window)

The cost of post-operative shed blood salvage after total knee arthroplasty: an analysis of 1,093 consecutive procedures. (opens new window)

Muñoz M, Ariza D, Campos A, Martín-Montañez E, Pavía J.

Forrás‎: Blood Transfus 2013;11(2):260-71.

Azonosító‎: PubMed 23149145

DOI‎: 10.2450/2012.0139-12

https://www.ncbi.nlm.nih.gov/pubmed/23149145 (opens new window)

Cost of post-operative intravenous iron therapy in total lower limb arthroplasty: a retrospective, matched cohort study. (opens new window)

Muñoz M, Gómez-Ramírez S, Martín-Montañez E, Naveira E, Seara J, Pavía J.

Forrás‎: Blood Transfus 2014;12(1):40-9.

Azonosító‎: PubMed 24120595

DOI‎: 10.2450/2013.0088-13

https://www.ncbi.nlm.nih.gov/pubmed/24120595 (opens new window)

Blood loss control with two doses of tranexamic acid in a multimodal protocol for total knee arthroplasty. (opens new window)

Ortega-Andreu M, Pérez-Chrzanowska H, Figueredo R, Gómez-Barrena E.

Forrás‎: Open Orthop J 2011;5:44-8.

Azonosító‎: PubMed 21552468

DOI‎: 10.2174/1874325001105010044

https://www.ncbi.nlm.nih.gov/pubmed/21552468 (opens new window)

ONTraC: A 20-year history of a successfully coordinated provincewide Patient Blood Management Program: lessons learned and goals achieved. (opens new window)

Pavenski K, Howell A, Mazer CD, Hare GMT, Freedman J.

Forrás‎: Anesth Analg 2022;135(3):448-58.

Azonosító‎: PubMed 35977355

DOI‎: 10.1213/ANE.0000000000006065

https://www.ncbi.nlm.nih.gov/pubmed/35977355 (opens new window)

Cost analysis of tranexamic acid in anemic total joint arthroplasty patients. (opens new window)

Phan DL, Ani F, Schwarzkopf R.

Forrás‎: J Arthroplasty 2016;31(3):579-82.

Azonosító‎: PubMed 26601635

DOI‎: 10.1016/j.arth.2015.10.001

https://www.ncbi.nlm.nih.gov/pubmed/26601635 (opens new window)

Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety. (opens new window)

Poeran J, Rasul R, Suzuki S, Danninger T, Mazumdar M, Opperer M, Boettner F, Memtsoudis SG.

Forrás‎: BMJ 2014;349:g4829.

Azonosító‎: PubMed 25116268

DOI‎: 10.1136/bmj.g4829

https://www.ncbi.nlm.nih.gov/pubmed/25116268 (opens new window)

One intraoperative dose of tranexamic acid for patients having primary hip or knee arthroplasty. (opens new window)

Ralley FE, Berta D, Binns V, Howard J, Naudie DD.

Forrás‎: Clin Orthop Relat Res 2010;468(7):1905-11.

Azonosító‎: PubMed 20063079

DOI‎: 10.1007/s11999-009-1217-8

https://www.ncbi.nlm.nih.gov/pubmed/20063079 (opens new window)

Pharmacologic hemostatic agents in total joint arthroplasty--a cost-effectiveness analysis. (opens new window)

Ramkumar DB, Ramkumar N, Tapp SJ, Moschetti WE.

Forrás‎: J Arthroplasty 2018;33(7):2092-9.e9.

Azonosító‎: PubMed 29605152

DOI‎: 10.1016/j.arth.2018.02.068

https://www.ncbi.nlm.nih.gov/pubmed/29605152 (opens new window)

Efficacy and cost-effectiveness of cell saving blood autotransfusion in adult lumbar fusion. (opens new window)

Savvidou C, Chatziioannou SN, Pilichou A, Pneumaticos SG.

Forrás‎: Transfus Med 2009;19(4):202-6.

Azonosító‎: PubMed 19706137

DOI‎: 10.1111/j.1365-3148.2009.00929.x

https://www.ncbi.nlm.nih.gov/pubmed/19706137 (opens new window)

Use of a fibrin sealant within a blood-saving protocol in patients undergoing revision hip arthroplasty: effects on post-operative blood transfusion and healthcare-related cost analysis. (opens new window)

Scardino M, Martorelli F, D'Amato T, Fenocchio G, Simili V, Grappiolo G, Di Matteo B, Kon E, Lagioia M

Forrás‎: Int Orthop 2019;43(12):2707-14.

Azonosító‎: PubMed 30671601

DOI‎: 10.1007/s00264-019-04291-4

https://www.ncbi.nlm.nih.gov/pubmed/30671601 (opens new window)

Use of tranexamic acid is a cost effective method in preventing blood loss during and after total knee replacement. (opens new window)

Sepah YJ, Umer M, Ahmad T, Nasim F, Chaudhry MU, Umar M.

Forrás‎: J Orthop Surg Res 2011;6:22.

Azonosító‎: PubMed 21600028

DOI‎: 10.1186/1749-799X-6-22

https://www.ncbi.nlm.nih.gov/pubmed/21600028 (opens new window)

Increased hospital costs associated with red blood cell transfusion. (opens new window)

Trentino KM, Farmer SL, Swain SG, Burrows SA, Hofmann A, Ienco R, Pavey W, Daly FF, Van Niekerk A, Webb SA, Towler S, Leahy MF.

Forrás‎: Transfusion 2015;55(5):1082-9.

Azonosító‎: PubMed 25488623

DOI‎: 10.1111/trf.12958

https://www.ncbi.nlm.nih.gov/pubmed/25488623 (opens new window)

Cost benefit analysis of topical tranexamic acid in primary total hip and knee arthroplasty. (opens new window)

Tuttle JR, Ritterman SA, Cassidy DB, Anazonwu WA, Froehlich JA, Rubin LE.

Forrás‎: J Arthroplasty 2014;29(8):1512-5.

Azonosító‎: PubMed 24630599

DOI‎: 10.1016/j.arth.2014.01.031

https://www.ncbi.nlm.nih.gov/pubmed/24630599 (opens new window)

Clinical and budget impact of treating preoperative anemia in major orthopedic surgery--a retrospective observational study. (opens new window)

Wan S, Sparring V, Cabrales DA, Jansson KÅ, Wikman A.

Forrás‎: J Arthroplasty 2020;35(11):3084-8.

Azonosító‎: PubMed 32654943

DOI‎: 10.1016/j.arth.2020.06.018

https://www.ncbi.nlm.nih.gov/pubmed/32654943 (opens new window)

Blood loss and cost-effectiveness of oral vs intravenous tranexamic acid in primary total hip arthroplasty: a randomized clinical trial. (opens new window)

Wu Y, Zeng Y, Hu Q, Li M, Bao X, Zhong J, Shen B.

Forrás‎: Thromb Res 2018;171:143-8.

Azonosító‎: PubMed 30312799

DOI‎: 10.1016/j.thromres.2018.10.006

https://www.ncbi.nlm.nih.gov/pubmed/30312799 (opens new window)

Incidence and costs of bleeding-related complications in French hospitals following surgery for various diagnoses. (opens new window)

Ye X, Lafuma A, Torreton E, Arnaud A.

Forrás‎: BMC Health Serv Res 2013;13:186.

Azonosító‎: PubMed 23692862

DOI‎: 10.1186/1472-6963-13-186

https://www.ncbi.nlm.nih.gov/pubmed/23692862 (opens new window)

The effectiveness of reinfusion after total knee replacement. A prospective randomised controlled study. (opens new window)

Zacharopoulos A, Apostolopoulos A, Kyriakidis A.

Forrás‎: Int Orthop 2007;31(3):303-8.

Azonosító‎: PubMed 16810542

DOI‎: 10.1007/s00264-006-0173-0

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Efficacy and safety of tranexamic acid in total hip replacement: a PRISMA-compliant meta-analysis of 25 randomized controlled trials. (opens new window)

Zhu J, Zhu Y, Lei P, Zeng M, Su W, Hu Y.

Forrás‎: Medicine 2017;96(52):e9552.

Azonosító‎: PubMed 29384974

DOI‎: 10.1097/MD.0000000000009552

https://www.ncbi.nlm.nih.gov/pubmed/29384974 (opens new window)